Serotonin transporter gene polymorphisms and sertraline response in major depression patients.

@article{Dogan2008SerotoninTG,
  title={Serotonin transporter gene polymorphisms and sertraline response in major depression patients.},
  author={Ozlem Ceylan Dogan and Nevzat Yuksel and Mehmet Ali Ergun and Akin Yilmaz and Mustafa Necmi Ilhan and Hatice Ersin Karslioglu and Aysegul Oruc Koc and Adnan Menevşe},
  journal={Genetic testing},
  year={2008},
  volume={12 2},
  pages={225-31}
}
Major depression (MD) has a complex multifactorial etiology with genetic and environmental factors contributing to the disorder. As with all antidepressant treatments, there is variability in drug response due to heredity, generally focusing on genetic polymorphism of the drug-metabolizing transporter genes. The serotonin transporter (5-HTT) gene is a particularly important candidate for genetic involvement in MD disorders owing to its key role in the regulation of serotonergic transmission and… CONTINUE READING

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Pharmacogenetics of selective serotonin reuptake inhibitor response in major depression

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Highly Influential
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