Serotonin transporter expression is predicted by early life stress and is associated with disinhibited behavior in infant rhesus macaques.

@article{Kinnally2010SerotoninTE,
  title={Serotonin transporter expression is predicted by early life stress and is associated with disinhibited behavior in infant rhesus macaques.},
  author={Erin L Kinnally and Erna R Tarara and W. Anthony Mason and Sally P. Mendoza and Kristina Abel and L. A. Lyons and John P Capitanio},
  journal={Genes, brain, and behavior},
  year={2010},
  volume={9 1},
  pages={45-52}
}
Serotonin transporter (5-HTT) expression patterns may contribute to the risk for adverse psychological outcomes following early life stress. The present study investigated whether two types of early life stress, maternal and social aggression, and a serotonin transporter gene promoter polymorphism (rh5-HTTLPR) predicted lower post-stressor peripheral blood mononuclear cell (PBMC) 5-HTT expression in infant rhesus macaques. We further probed the relationships among these factors and infant… CONTINUE READING

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