Serotonin receptors involved in antidepressant effects.

  title={Serotonin receptors involved in antidepressant effects.},
  author={Francesc Casa{\~n}as Artigas},
  journal={Pharmacology & therapeutics},
  volume={137 1},
The neurotransmitter serotonin (5-hdroxytryptamine; 5-HT) has been implicated in the pathophysiology and treatment of major depression since the serendipitous discovery of antidepressant drugs in the 1950s. However, despite the generalised use of serotonin-enhancing drugs, such as the selective serotonin reuptake inhibitors (SSRIs) and the dual serotonin… CONTINUE READING