Serotonin receptor (5-HT 2A) and catechol-O-methyltransferase (COMT) gene polymorphisms: triggers of fibromyalgia?

  title={Serotonin receptor (5-HT 2A) and catechol-O-methyltransferase (COMT) gene polymorphisms: triggers of fibromyalgia?},
  author={Josie Budag Matsuda and Fl{\'a}via Regina Pinho Barbosa and Lucas Junqueira Fernandes Morel and Suzelei de Castro França and S{\^o}nia Marli Zingaretti and Lucienir Maria da Silva and Ana Maria Soares Pereira and Mozart Marins and Ana L{\'u}cia Fachin},
  journal={Revista brasileira de reumatologia},
  volume={50 2},
INTRODUCTION Fibromyalgia is a rheumatic syndrome characterized by diffuse and chronic pain associated with fatigue, sleep disorders, anxiety, depression, memory loss, and dizziness. Although the physiological mechanisms that control fibromyalgia have not been precisely established, neuroendocrine, genetic or molecular factors may be involved in fibromyalgia. OBJECTIVE The aim of the present study was to characterize serotonin receptor (5-HT2A) and catechol-O-methyltransferase (COMT) gene… CONTINUE READING
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Catechol-O-Methyl Transferase (COMT) gene haplotypes in Mexican and Spaniard patients with fibromyalgia

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