Serotonin modulates responses to species-specific vocalizations in the inferior colliculus

@article{Hurley2005SerotoninMR,
  title={Serotonin modulates responses to species-specific vocalizations in the inferior colliculus},
  author={Laura M. Hurley and George D. Pollak},
  journal={Journal of Comparative Physiology A},
  year={2005},
  volume={191},
  pages={535-546}
}
  • L. Hurley, G. Pollak
  • Published 14 April 2005
  • Biology, Psychology
  • Journal of Comparative Physiology A
Neuromodulators such as serotonin are capable of altering the neural processing of stimuli across many sensory modalities. In the inferior colliculus, a major midbrain auditory gateway, serotonin alters the way that individual neurons respond to simple tone bursts and linear frequency modulated sweeps. The effects of serotonin are complex, and vary among neurons. How serotonin transforms the responses to spectrotemporally complex sounds of the type normally heard in natural settings has been… 

Different serotonin receptor agonists have distinct effects on sound-evoked responses in inferior colliculus.

  • L. Hurley
  • Biology, Psychology
    Journal of neurophysiology
  • 2006
TLDR
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References

SHOWING 1-10 OF 66 REFERENCES

Serotonin effects on frequency tuning of inferior colliculus neurons.

TLDR
The results suggest that serotonin, whose release varies with behavioral state, functionally reconfigures the circuitry of the IC and may modulate the perception of acoustic signals under different behavioral states.

Serotonin Differentially Modulates Responses to Tones and Frequency-Modulated Sweeps in the Inferior Colliculus

TLDR
The results suggest that the population activity evoked by a particular sound is not simply a consequence of the hard wiring that connects the IC to lower and higher regions but rather is highly dynamic because of the functional reconfigurations induced by serotonin and almost certainly other neuromodulators as well.

Serotonin in the inferior colliculus

Representation of species-specific vocalizations in the inferior colliculus of the guinea pig.

TLDR
This study provides evidence for the encoding of the spectrotemporal acoustic patterns of vocalizations by IC units by recording the responses of individual neurons to guinea pig vocalization calls.

Spectral determination of responses to species-specific calls in the dorsal nucleus of the lateral lemniscus.

TLDR
It is shown that DNLL responses evoked by complex sounds can be largely explained by a simple summation of the excitation in each neuron's ERR, and that the DNLL population response re-creates both the spectral and the temporal features of each signal.

Processing and representation of species-specific communication calls in the auditory system of bats.

Differential representation of species-specific primate vocalizations in the auditory cortices of marmoset and cat.

TLDR
Differential representation of marmoset vocalizations in two cortices suggests that experience-dependent and possibly species-specific mechanisms are involved in cortical processing of communication sounds.

Response selectivity for species-specific calls in the inferior colliculus of Mexican free-tailed bats is generated by inhibition.

TLDR
The inhibition evoked by each call can shape a unique pattern of activity in the IC population and that pattern may be important for both the identification of a particular call and for discriminating it from other calls and other signals.

Serotonin modulates auditory information processing in the cochlear nucleus of the rat

...