Serotonin metabolism in rat mesangial cells: involvement of a serotonin transporter and monoamine oxidase A.

Abstract

BACKGROUND Serotonin is one of the factors regulating mesangial cell proliferation, and convergent evidence supports its involvement in the development of glomerulonephritis. In this study, we identified a serotonin transporter and the amine-degrading enzyme monoamine oxidases (MAOs) in mesangial cells, and we studied their involvement in serotonin… (More)

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