Serotonin mediates cross modal reorganization of cortical circuit

@article{Jitsuki2009SerotoninMC,
  title={Serotonin mediates cross modal reorganization of cortical circuit},
  author={Susumu Jitsuki and Toshitada Takahashi},
  journal={Neuroscience Research},
  year={2009},
  volume={65}
}
s S67 RET signaling in vitro, we engineered Ret locus to allow elevated levels of Bcl-xL expression in ENCDCs, and assessed the degree of contribution of cell death to the emergence of aganglionosis in the HSCR model mice. Now, we have demonstrated that Bcl-xL overexpression reduced enteric neuronal loss in the colon induced by Ret ablation and rescue enteric neurons from colonic aganglionosis in the HSCR model mice. These results strongly suggest that cell death principally causes isolated… CONTINUE READING
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