Serotonin mediated immunoregulation and neural functions: Complicity in the aetiology of autism spectrum disorders

@article{Jaiswal2015SerotoninMI,
  title={Serotonin mediated immunoregulation and neural functions: Complicity in the aetiology of autism spectrum disorders},
  author={Preeti Jaiswal and Kochupurackal P. Mohanakumar and Usha Rajamma},
  journal={Neuroscience & Biobehavioral Reviews},
  year={2015},
  volume={55},
  pages={413-431}
}
Serotonergic system has long been implicated in the aetiology of autism spectrum disorders (ASD), since platelet hyperserotonemia is consistently observed in a subset of autistic patients, who respond well to selective serotonin reuptake inhibitors. Apart from being a neurotransmitter, serotonin functions as a neurotrophic factor directing brain development and as an immunoregulator modulating immune responses. Serotonin transporter (SERT) regulates serotonin level in lymphoid tissues to ensure… CONTINUE READING
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