Serotonin in autism and pediatric epilepsies.

  title={Serotonin in autism and pediatric epilepsies.},
  author={Diane C. Chugani},
  journal={Mental retardation and developmental disabilities research reviews},
  volume={10 2},
  • Diane C. Chugani
  • Published 2004 in
    Mental retardation and developmental disabilities…
Serotonergic abnormalities have been reported in both autism and epilepsy. This association may provide insights into underlying mechanisms of these disorders because serotonin plays an important neurotrophic role during brain development--and there is evidence for abnormal cortical development in both autism and some forms of epilepsy. This review explores the hypothesis that an early disturbance in the serotonin system affects cortical development and the development of thalamocortical… CONTINUE READING

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