Serotonin-dependent collagenase induction in rat myometrial smooth muscle cells: mediation by the 5-HT2 receptor.

@article{RydelekFitzgerald1993SerotonindependentCI,
  title={Serotonin-dependent collagenase induction in rat myometrial smooth muscle cells: mediation by the 5-HT2 receptor.},
  author={Laura Rydelek-Fitzgerald and Brian D Wilcox and Milt Teitler and John M. Jeffrey},
  journal={Molecular and cellular endocrinology},
  year={1993},
  volume={91 1-2},
  pages={67-74}
}
Recent studies have shown that serotonin (5-hydroxytryptamine; 5-HT) is required for the induction of interstitial collagenase in cultured rat and human myometrial smooth muscle cells. The present study was performed to determine which serotonin receptor subtype mediates the induction of collagenase in these cells. [125I]DOI ((+/- )-1-(2,5-dimethoxy-4-[125I… CONTINUE READING