Serotonin and its antidepressant-sensitive transport in mouse cumulus-oocyte complexes and early embryos.

@article{Amireault2005SerotoninAI,
  title={Serotonin and its antidepressant-sensitive transport in mouse cumulus-oocyte complexes and early embryos.},
  author={Pascal Amireault and François Dub{\'e}},
  journal={Biology of reproduction},
  year={2005},
  volume={73 2},
  pages={358-65}
}
Serotonin (5-hydroxytryptamine [5-HT]), is a neurohormone found in various nonneural tissues, including the gonads of many invertebrates, in which it regulates spawning and oocyte meiotic maturation. The possibility that a local serotonergic network might also exist in the female gonads of vertebrate species, including mammals, remains poorly documented. To clarify this possibility, we investigated mouse cumulus cells, oocytes, and embryos for three key serotonergic components, namely, 5-HT… CONTINUE READING

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