Serotonin and Migraine: Biology and Clinical Implications

@article{Hamel2007SerotoninAM,
  title={Serotonin and Migraine: Biology and Clinical Implications},
  author={E. Hamel and Headache Currents},
  journal={Cephalalgia},
  year={2007},
  volume={27},
  pages={1293 - 1300}
}
Migraine is the most frequent neurological disorder in the adult population worldwide, affecting up to 12% of the general population and more frequent in women (~25%). It has a high impact on our society due to its disabling nature and, therein, reduced quality of life and increased absenteeism from work. Headache is the primary clinical manifestation and it has been associated with ‘a hereditary or predisposed sensitivity of neurovascular reactions to certain stimuli or to cyclic changes in… Expand
254 Citations
The Biology of the Glutamatergic System and Potential Role in Migraine
  • 18
  • PDF
Platelets and migraine.
  • 31
Serotonin and migraine: a reconsideration of the central theory
  • 90
  • Highly Influenced
  • PDF
Molecular factors in migraine
  • 24
  • PDF
Serotonergic mechanisms in the migraine brain – a systematic review
  • 40
Does the Neurobiology of Migraine Make Migraine Patients “Difficult”?
  • 1
Pathophysiological Bases of Comorbidity in Migraine
  • Highly Influenced
Serotonin in Neurological Diseases
  • PDF
ASICs as therapeutic targets for migraine
  • 40
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 64 REFERENCES
The biology of serotonin receptors: focus on migraine pathophysiology and treatment.
  • E. Hamel
  • Medicine
  • The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
  • 1999
  • 48
  • PDF
On Serotonin and Migraine: A Clinical and Pharmacological Review
  • 206
  • PDF
5-Hydroxytryptamine and the pathophysiology of migraine
  • 63
Increased brain serotonin synthesis in migraine.
  • 118
Increased serotonin transporter availability in the brainstem of migraineurs
  • 58
Current concepts of migraine pathogenesis.
  • 86
...
1
2
3
4
5
...