Serotonin Transporter Residual Availability During Long-Term Antidepressant Therapy Does Not Differentiate Responder and Nonresponder Unipolar Patients

@article{Cavanagh2006SerotoninTR,
  title={Serotonin Transporter Residual Availability During Long-Term Antidepressant Therapy Does Not Differentiate Responder and Nonresponder Unipolar Patients},
  author={Jonathan Cavanagh and James Patterson and Sally Pimlott and Deborah Dewar and David Wyper},
  journal={Biological Psychiatry},
  year={2006},
  volume={59},
  pages={301-308}
}
BACKGROUND Serotonin transporters (SERT) are a major target for antidepressant medication, although there have been limited in vivo studies of SERT availability in patients being treated with antidepressants. It is not known whether SERT availability differs in treatment-responsive and -nonresponsive patients receiving long-term treatment. In this study, we used single photon emission computed tomography (SPECT) to compare SERT residual availability in unipolar responders and nonresponders… CONTINUE READING

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