Serotonin 2C receptor alternative splicing in a spinal cord injury model

@article{Nakae2013Serotonin2R,
  title={Serotonin 2C receptor alternative splicing in a spinal cord injury model},
  author={Aya Nakae and Katsuhiko Nakai and Tatsuya Tanaka and Ko Hosokawa and Takashi Mashimo},
  journal={Neuroscience Letters},
  year={2013},
  volume={532},
  pages={49-54}
}
Spinal cord injury can have debilitating consequences, commonly resulting in motor dysfunction below the lesion site and the development of chronic pain syndromes. The serotonin pathway is important for inhibiting noxious stimuli and facilitating motor function after spinal cord injury. The serotonin 2C receptor (5HTR2C) has several characteristic features, and is regulated by the amount of serotonin 2C receptor as well as RNA editing and alternative splicing. In this study, we used a rat model… CONTINUE READING
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