Serotonin 1B receptor imaging in pathological gambling.

  title={Serotonin 1B receptor imaging in pathological gambling.},
  author={Marc N. Potenza and Espen Walderhaug and Shannan Henry and Jean-Dominique Gallezot and Beata Planeta-Wilson and Jim R Ropchan and Alexander Neumeister},
  journal={The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry},
  volume={14 2},
Abstract Objectives. Although serotonergic mechanisms have been implicated in pathological gambling (PG), no ligand-based imaging studies have assessed serotonin receptors in individuals with PG. Given its role in substance addictions and its abundance in brain regions implicated in PG, we evaluated serotonin 1B receptors (5-HT1BRs) in PG. Methods. Ten medication-free subjects with PG (mean ± SD age = 36.3 ± 9.4 years, nine men) and ten control comparison (CC) subjects (mean ± SD age = 35.8 ± 9… CONTINUE READING