Serotonin 1A receptor gene and major depressive disorder: an association study and meta-analysis

@article{Kishi2009Serotonin1R,
  title={Serotonin 1A receptor gene and major depressive disorder: an association study and meta-analysis},
  author={Taro Kishi and Tomoko Tsunoka and M Ikeda and Kunihiro Kawashima and Tomo Okochi and Tsuyoshi Kitajima and Yoko Kinoshita and Takenori Okumura and Yoshio Yamanouchi and Toshiya Inada and Norio Ozaki and Nakao Iwata},
  journal={Journal of Human Genetics},
  year={2009},
  volume={54},
  pages={629-633}
}
Several genetic studies have shown an association between the 5-HT1A receptor gene (HTR1A) and major depressive disorder (MDD); however, results have been rather inconsistent. Moreover, to our knowledge, no association study on HTR1A and MDD in the Japanese population has been reported. Therefore, to evaluate the association between HTR1A and MDD, we conducted a case–control study of Japanese population samples with two single-nucleotide polymorphisms (SNPs), including rs6295 (C-1019G) in HTR1A… CONTINUE READING