Serotonin-1A receptor activation in hippocampal CA1 neurons by 8-hydroxy-2-(di-n-propylamino)tetralin, 5-methoxytryptamine and 5-hydroxytryptamine

@article{Wu1988Serotonin1ARA,
  title={Serotonin-1A receptor activation in hippocampal CA1 neurons by 8-hydroxy-2-(di-n-propylamino)tetralin, 5-methoxytryptamine and 5-hydroxytryptamine},
  author={P. H. Wu and Nataly Gurevich and Peter L. Carlen},
  journal={Neuroscience Letters},
  year={1988},
  volume={86},
  pages={72-76}
}
Effects of 5-hydroxytryptamine on the firing rates of neurons of the lateral vestibular nucleus in the rat
TLDR
It is demonstrated that 5-HT modifies the responsiveness of vestibular neurons and suggest that at least two mechanisms and maybe two types of receptors are activated by 5- HT in this nucleus.
5‐HT1A Receptors and 5‐HT1A‐Mediated Responses: Effect of Treatments That Modify Serotonergic Neurotransmission
TLDR
Repeated treatment of rats with the lipophilic partial PZ agonist clenbuterol reduces the density of P-adrenoceptors throughout the central nervous system (CNS), and it is found that intraventricular administration of the full P- adrenoceptor agonist, isoproterenol, decreased thedensity of BARs, particularly the P2 subtype, in many areas of brain.
Actions of 5‐HT1 ligands on excitatory synaptic transmission in the hippocampus of alert rats
TLDR
It is concluded that hippocampal synaptic transmission is highly sensitive to the agonist and antagonist properties of 5‐HT1 ligands in the alert rat.
The biophysical and pharmacological properties of presumptive serotonergic neurones recorded intracellularly from the dorsal raphe nucleus in the in vitro slice preparation
TLDR
The selective 5-HT^ agonists 8hydroxy-2-(di-n-propylamino)teralin (8-OHDPAT), dipropylcarboxamidotryptamine (DP-5-CT) and the novel anxiolytic buspirone caused a marked longlasting hyperpolarisation with an associated decrease in Rm and r at concentrations lower than required for an equivalent response to 5- HT.
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