Serotonergic versus nonserotonergic dorsal raphe projection neurons: differential participation in reward circuitry.

@article{Mcdevitt2014SerotonergicVN,
  title={Serotonergic versus nonserotonergic dorsal raphe projection neurons: differential participation in reward circuitry.},
  author={Ross A Mcdevitt and Alix Tiran-Cappello and Hui Shen and Israela Balderas and Jonathan P Britt and Rosa Anna Maria Marino and Stephanie L Chung and Christopher T Richie and Brandon K. Harvey and Antonello Bonci Bonci},
  journal={Cell reports},
  year={2014},
  volume={8 6},
  pages={1857-1869}
}
The dorsal raphe nucleus (DRN) contains the largest group of serotonin-producing neurons in the brain and projects to regions controlling reward. Although pharmacological studies suggest that serotonin inhibits reward seeking, electrical stimulation of the DRN strongly reinforces instrumental behavior. Here, we provide a targeted assessment of the behavioral, anatomical, and electrophysiological contributions of serotonergic and nonserotonergic DRN neurons to reward processes. To explore DRN… CONTINUE READING