Serotonergic system and attention deficit hyperactivity disorder (ADHD): a potential susceptibility locus at the 5-HT1B receptor gene in 273 nuclear families from a multi-centre sample

@article{Hawi2002SerotonergicSA,
  title={Serotonergic system and attention deficit hyperactivity disorder (ADHD): a potential susceptibility locus at the 5-HT1B receptor gene in 273 nuclear families from a multi-centre sample},
  author={Ziarih Hawi and Michael Dring and Aiveen Kirley and Diane Foley and Lindsey Kent and Nicholas John Craddock and P Asherson and Sarah Curran and Alicia Gould and Sandra L. Richards and Deborah C. Lawson and H. Pay and Darko Turic and Kate Langley and Michael J. Owen and Michael Conlon O'Donovan and Anita Thapar and Michael Fitzgerald and M Gill},
  journal={Molecular Psychiatry},
  year={2002},
  volume={7},
  pages={718-725}
}
Attention deficit hyperactivity disorder (ADHD) is a highly heritable and heterogeneous disorder, which usually becomes apparent during the first few years of childhood. Imbalance in dopamine neurotransmission has been suggested as a factor predisposing to ADHD. However, evidence has suggested an interaction between dopamine and serotonin systems in the pathophysiology of the disorder. Studies using selective agonists of the different 5-HT receptors microinjected into selected brain structures… CONTINUE READING

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