Serotonergic regulation of blood glucose levels in the crayfish, Procambarus clarkii: site of action and receptor characterization.

@article{Lee2000SerotonergicRO,
  title={Serotonergic regulation of blood glucose levels in the crayfish, Procambarus clarkii: site of action and receptor characterization.},
  author={C Y Lee and Siu Yau and Chiau S Liau and Wei Huang},
  journal={The Journal of experimental zoology},
  year={2000},
  volume={286 6},
  pages={596-605}
}
The present study investigated the site of action of 5-hydroxytryptamine (5-HT) and pharmacologically characterized the receptors involved in regulating blood glucose levels in the crayfish, Procambarus clarkii. Injection of 5-HT into intact animals increased glucose levels in a dose-dependent manner. In contrast, 5-HT failed to elicit a hyperglycemic response in eyestalk-ablated animals. Effects of several 5-HT receptor agonists and antagonists were examined. 5-CT, oxymetazoline (both 5-HT(1… CONTINUE READING

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