Serotonergic receptor antagonist from Nandina domestica Thunberg.


A crude methanolic extract of the fruit of Nandina domestica Thunberg strongly inhibits serotonin-induced contractions of the rabbit aorta. The extract of the fruit has been fractionated to afford nantenine (O- methyldomesticine ) as the active agent. 


Cite this paper

@article{Shoji1984SerotonergicRA, title={Serotonergic receptor antagonist from Nandina domestica Thunberg.}, author={Naoko Shoji and Akemi Umeyama and Toshinobu Takemoto and Yukio Ohizumi}, journal={Journal of pharmaceutical sciences}, year={1984}, volume={73 4}, pages={568-70} }