Serotonergic neurotransmission in the living human brain: a positron emission tomography study using [¹¹C]dasb and [¹¹C]WAY100635 in young healthy men.

@article{Takano2011SerotonergicNI,
  title={Serotonergic neurotransmission in the living human brain: a positron emission tomography study using [¹¹C]dasb and [¹¹C]WAY100635 in young healthy men.},
  author={Harumasa Takano and Hiroshi Ito and Hidehiko Takahashi and Ryosuke Arakawa and Masaki Okumura and Fumitoshi Kodaka and Tatsui Otsuka and Motoichiro Kato and Tetsuya Suhara},
  journal={Synapse},
  year={2011},
  volume={65 7},
  pages={624-33}
}
The central serotonergic (5-HT) system is closely involved in regulating various mental functions such as mood and emotion. In this system, the serotonin transporter (5-HTT) and the 5-HT(1A) receptor play important roles in the pathophysiology and treatment of mood and anxiety disorders. However, only a few integrated databases have considered the intraindividual relationship between pre- and postsynaptic serotonergic transmission. In the present study, we constructed a database of 5-HTT and 5… CONTINUE READING
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