Serotonergic mechanisms in brains of suicide victims

@article{Owen1986SerotonergicMI,
  title={Serotonergic mechanisms in brains of suicide victims},
  author={Frances Owen and David R. Chambers and Sybil Jane Cooper and Timothy John Crow and Mark A. Poulter},
  journal={Brain Research},
  year={1986},
  volume={362},
  pages={185-188}
}
Serotonergic mechanisms have been investigated in postmortem brain samples from controls and suicide victims. The concentrations of 5-hydroxytryptamine (serotonin; 5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) were determined in occipital cortex and hippocampus and the high-affinity binding of ligands to the 5-HT1, 5-HT2 and imipramine-binding sites was assessed in frontal cortex, occipital cortex and hippocampus. The only significant difference between the two groups was a modest increase in 5… CONTINUE READING
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