Serotonergic innervation of the pituitary pars intermedia of xenopus laevis.

@article{Ubink1999SerotonergicIO,
  title={Serotonergic innervation of the pituitary pars intermedia of xenopus laevis.},
  author={Ruud Ubink and Marina Buzzi and Peter M J M Cruijsen and Rienk Tuinhof and Albert A. J. Verhofstad and Bruce G. Jenks and Eric W. Roubos},
  journal={Journal of neuroendocrinology},
  year={1999},
  volume={11 3},
  pages={211-9}
}
At this point three brain centres are thought to be involved in the regulation of the melanotrope cells of the pituitary pars intermedia of Xenopus laevis: the magnocellular nucleus, the suprachiasmatic nucleus and the locus coeruleus. This study aims to investigate the existence of a fourth, serotonergic, centre controlling the melanotrope cells. In-vitro superfusion studies show that serotonin has a dose-dependent stimulatory effect on peptide release (1.6 x basal level at 10(-6) M serotonin… CONTINUE READING