Serotonergic function and self-injurious behavior in personality disorder patients.

  title={Serotonergic function and self-injurious behavior in personality disorder patients.},
  author={Antonia S. New and Robert L. Trestman and Vivian Mitropoulou and D S Benishay and Emil F. Coccaro and Jeremy Silverman and Larry J. Siever},
  journal={Psychiatry research},
  volume={69 1},
Self-directed aggression, whether in the form of non-suicidal self-mutilation or suicidal behavior, is a prominent feature of personality disorders. We hypothesized that self-injurious behavior, like suicidal behavior, represents a form of self-directed aggression, and may, like suicidal behavior and impulsive aggression, be associated with a decrease in central serotonin function in personality disorder patients. Ninety-seven patients with DSM-III personality disorder underwent D,L… CONTINUE READING


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