Serotonergic and cholinergic inhibition of mesopontine cholinergic neurons controlling REM sleep: an in vitro electrophysiological study.


Intracellular recordings were obtained from neurons of the laterodorsal tegmental and pedunculopontine tegmental nuclei in a brain-slice preparation. The action of exogenously applied 5-hydroxytryptamine and acetylcholine was studied on NADPH-diaphorase-labeled cells which contain nitric oxide synthase and are presumed to be cholinergic. Our results… (More)


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