Serotonergic Mechanisms Influence the Response to Glucocorticoid Treatment in TMJ Arthritis

@article{Fredriksson2005SerotonergicMI,
  title={Serotonergic Mechanisms Influence the Response to
Glucocorticoid Treatment in TMJ Arthritis},
  author={Lars A. Fredriksson and P Alstergren and Sigvard Kopp},
  journal={Mediators of Inflammation},
  year={2005},
  volume={2005},
  pages={194 - 201}
}
The aims of this study were to investigate the influence of serotonin (5-HT) on the effects of intra-articular injections of glucocorticoid on pain of the temporomandibular joint (TMJ) in patients with inflammatory disorders of the TMJ. The pretreatment synovial fluid 5-HT was negatively, and plasma 5-HT positively, correlated to change in TMJ pain after treatment. The pretreatment plasma 5-HT was positively correlated to change in pressure-pain threshold after treatment. In conclusion, this… CONTINUE READING

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