Seroprevalence of Streptococcal Inhibitor of Complement (SIC) suggests association of streptococcal infection with chronic kidney disease

@inproceedings{Karmarkar2013SeroprevalenceOS,
  title={Seroprevalence of Streptococcal Inhibitor of Complement (SIC) suggests association of streptococcal infection with chronic kidney disease},
  author={Mohan Ganesh Karmarkar and Gouri Pandharinath Hule and Niwrutti Khandu Hase and Preeti Rajeev Mehta and Scott R. Walter and Kadaba Srinivasa Sriprakash},
  booktitle={BMC nephrology},
  year={2013}
}
BACKGROUND Group A streptococcus (GAS) is an etiological agent for the immune mediated sequela post streptococcal glomerulonephritis (PSGN). In some populations PSGN is recognized as a risk factor for chronic kidney disease (CKD) and end-stage renal disease (ESRD). It was found that a significantly greater proportion of subjects with past history of PSGN than without the history exhibited seroreactions to streptococcal antigens called streptococcal inhibitor of complement (SIC) and to distantly… CONTINUE READING
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