Seronegative Necrolytic Acral Erythema: a Distinct Clinical Subset?

  title={Seronegative Necrolytic Acral Erythema: a Distinct Clinical Subset?},
  author={Saumya Panda and Koushik Lahiri},
  booktitle={Indian journal of dermatology},
A patient was referred to us with asymptomatic, erythematous, nonitchy, scaly lesions present bilaterally on the dorsa of his feet and toes since the last 2 months. Both the legs had pitting edema as well. There were hyperkeratosis, focal parakeratosis, acanthosis and scattered spongiosis in the epidermis, and proliferation of capillaries with perivascular infiltration of lymphomononuclear cells in the dermis. There was no serological evidence of hepatitis C virus. Laboratory investigations… CONTINUE READING