Serological pancreatic tumor markers and the MUC1 apomucin.

  title={Serological pancreatic tumor markers and the MUC1 apomucin.},
  author={Jenny J. L. Ho and Young Ju Kim},
  volume={9 6},
Over 80% of adenocarcinomas of the pancreas originate from duct cells, which are the major source of mucins in the pancreas. Pathological conditions produce changes in the composition and structure of the oligosaccharides of colonic and pancreatic mucins, and it has been suggested that mucins may have a role in the detection of pancreatic cancer. Mucins are now the targets of a number of immunodiagnostic assays for cancer, and their possible use in therapy is being studied. This review… CONTINUE READING
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