Serological diagnosis of Chagas' disease: a potential confirmatory assay using preserved protein antigens of Trypanosoma cruzi.

@article{Mendes1997SerologicalDO,
  title={Serological diagnosis of Chagas' disease: a potential confirmatory assay using preserved protein antigens of Trypanosoma cruzi.},
  author={Rinaldo P Mendes and Sumie Hoshino-Shimizu and Ana Maria Moura da Silva and Iv{\'a}n A. Estrada Mota and Ramiro Heredia and Alejandro Ostermayer Luquetti and Paulo Guilherme Leser},
  journal={Journal of clinical microbiology},
  year={1997},
  volume={35 7},
  pages={1829-34}
}
The diagnosis of Chagas' disease relies mostly on data provided by immunologic tests, but inconclusive results often require elucidation, especially in blood banks. When six different types of Trypanosoma cruzi epimastigote antigens were studied by an immunoblotting assay (IBA), a preserved protein antigen (Ag PP) was found to present the most interesting immunochemical features because of its high reactivity with anti-T. cruzi antibodies. Thus, the IBA with Ag PP (PP IBA) was assessed with… CONTINUE READING

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