Serological characterization of surface-exposed proteins of Coxiella burnetii.

@article{Jiao2014SerologicalCO,
  title={Serological characterization of surface-exposed proteins of Coxiella burnetii.},
  author={Jun Jiao and Xiaolu Xiong and Yong Qi and Wenping Gong and Changsong Duan and Xiaomei Yang and Bohai Wen},
  journal={Microbiology},
  year={2014},
  volume={160 Pt 12},
  pages={
          2718-31
        }
}
The obligate intracellular Gram-negative bacterium Coxiella burnetii causes Q fever, a worldwide zoonosis. [] Key Method Using two-dimensional electrophoresis combined with mass spectrometry, we identified 37 proteins through bioinformatics analysis. Thirty SEPs expressed in Escherichia coli (recombinant SEPs, rSEPs) were used to generate microarrays, which were probed with sera from mice experimentally infected with Cox. burnetii or sera from Q fever patients. Thirteen rSEPs were recognized as seroreactive…

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