Serological characteristics of partial D antigen category VI in 8 unrelated blood donors.

Abstract

Classification of subjects with a partial D antigen is traditionally performed with immune anti-D sera. The development of monoclonal antibodies enables a fine analysis to be made of the specificity of the epitopes that are present or missing in these cases. A systematic search in a Caucasian donor population of 17,500 revealed 8 unrelated male individuals (frequency 0.05%) with a red cell phenotype characteristic of partial D category VI, but without anti-D in their serum. The relation to the 'classic' partial D category VI was investigated and is discussed, as is the observed serological heterogeneity of the partial D category VI group. Clinical consequences for the prevention of immunization of these subjects are mentioned.

Statistics

0200400'96'98'00'02'04'06'08'10'12'14'16
Citations per Year

136 Citations

Semantic Scholar estimates that this publication has 136 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Rhenen1994SerologicalCO, title={Serological characteristics of partial D antigen category VI in 8 unrelated blood donors.}, author={Dick van Rhenen and Pieter Thijssen and Marijke A M Overbeeke}, journal={Vox sanguinis}, year={1994}, volume={66 2}, pages={133-6} }