Serological and virological assessment of oral and inactivated poliovirus vaccines in a rural population in Kenya.

  title={Serological and virological assessment of oral and inactivated poliovirus vaccines in a rural population in Kenya.},
  author={P W Kok and J. Leeuwenburg and Peter M. Tukei and A L van Wezel and Jacoba G. Kapsenberg and G J van Steenis and Alicja Galazka and S. E. Robertson and David Robinson},
  journal={Bulletin of the World Health Organization},
  volume={70 1},
A study was carried out in a rural community in Kenya to compare the humoral and intestinal immunity provided by three doses of oral poliovirus vaccine (OPV) and two or three doses of enhanced-potency inactivated poliovirus vaccine (IPV). The immunization series was started at 8-12 weeks of age and the interval between doses was 2 months. In children with low levels of maternal antibodies (i.e., those most at risk), the first dose of either vaccine stimulated antibody response. Children with… CONTINUE READING


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