Serological Proteome Analysis (SERPA) as a tool for the identification of new candidate autoantigens in type 1 diabetes.

@article{Massa2013SerologicalPA,
  title={Serological Proteome Analysis (SERPA) as a tool for the identification of new candidate autoantigens in type 1 diabetes.},
  author={Ornella Massa and Massimo Alessio and Lucia Russo and Giovanni Nardo and Valentina Bonetto and F. Bertuzzi and Alessandra Paladini and Dario Iafusco and Patrizia Ippolita Patera and Giorgio Federici and Tarcisio Not and Claudio Tiberti and Riccardo Bonfanti and Fabrizio Barbetti},
  journal={Journal of proteomics},
  year={2013},
  volume={82},
  pages={263-73}
}
UNLABELLED Type 1 diabetes (T1D) is an autoimmune disease characterized by the presence of circulating autoantibodies directed against proteins of islet beta-cell. Autoantibody testing is used for diagnostic purposes; however, up to 2-5% of patients who are clinically diagnosed with T1D are found negative for known antibodies, suggesting that the T1D… CONTINUE READING