Serologic diagnosis of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis through the detection of immunoglobulin G to Aspergillus fumigatus.

@article{Barton2008SerologicDO,
  title={Serologic diagnosis of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis through the detection of immunoglobulin G to Aspergillus fumigatus.},
  author={Richard C. Barton and Richard Hobson and Miles Denton and Daniel Peckham and Keith Brownlee and Steven Conway and Michael A. Kerr},
  journal={Diagnostic microbiology and infectious disease},
  year={2008},
  volume={62 3},
  pages={287-91}
}
Allergic bronchopulmonary aspergillosis (ABPA) is seen in approximately 10% of patients with cystic fibrosis (CF) and can be difficult to diagnose. Consensus criteria require the presence of multiple elevated immunologic markers such as total immunoglobulin E (IgE), Aspergillus IgE and Aspergillus IgG, or precipitins for a robust diagnosis. There is some degree of standardization of total IgE and Aspergillus IgE levels, but there is no standardization in the measurement of IgG antibodies or… CONTINUE READING

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