Serologic cross-reactivities poorly reflect allelic relationships in the HLA-B12 and HLA-B21 groups. Dominant epitopes of the alpha 2 helix.

@article{Hildebrand1992SerologicCP,
  title={Serologic cross-reactivities poorly reflect allelic relationships in the HLA-B12 and HLA-B21 groups. Dominant epitopes of the alpha 2 helix.},
  author={William H. Hildebrand and Jos{\`e} Alejandro Madrigal and M{\^o}nica P. Belich and Jacqueline Zemmour and Frances E. Ward and Robert Charles Williams and Peter Parham},
  journal={Journal of immunology},
  year={1992},
  volume={149 11},
  pages={3563-8}
}
Previous analysis has emphasized the correlation between primary structures of class I HLA molecules and their patterns of serologic cross-reactivity. Here we describe the structures of two serologic groups of HLA-B alleles for which this is not the case. HLA-B45, an allele associated with black populations, is serologically paired with B44 in the B12 group… CONTINUE READING