Serologic cross-reactions among Ehrlichia equi, Ehrlichia phagocytophila, and human granulocytic Ehrlichia.

@article{Dumler1995SerologicCA,
  title={Serologic cross-reactions among Ehrlichia equi, Ehrlichia phagocytophila, and human granulocytic Ehrlichia.},
  author={John Stephen Dumler and K M Asanovich and Johan S. Bakken and Philip J. Richter and Robert B. Kimsey and John E. Madigan},
  journal={Journal of clinical microbiology},
  year={1995},
  volume={33 5},
  pages={
          1098-103
        }
}
Homology in the 16S rDNAs shows that the agent of human granulocytic ehrlichiosis (HGE) is closely related to the veterinary pathogens Erlichia equi and Erlichia phagocytophila. After HGE, patients develop antibodies reactive with E. equi and E. phagocytophila; thus, we hypothesized that these species are closely related and share significant antigenicity. Antisera from humans, horses, dogs, and cattle were tested by indirect fluorescent-antibody assay (IFA) for antibodies reactive with E. equi… CONTINUE READING

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