Serogroup C meningococcal disease outbreak associated with discotheque attendance during carnival.


In the week following a carnival during 19-24 February 1998, an outbreak of meningococcal disease occurred in a rural German county. The available isolates belonged to phenotype C:2a:P1.2,5 and were clonally related by pulsed-field gel electrophoresis. A case-control study was done to identify risk factors for the outbreak and to define possible vaccination target groups. Five persons aged 13-16 years who fell ill during 24-27 February were included in the study. Four of 5 cases and 10 of 32 controls visited local discotheques (OR = 8.8; P = 0.06). Cases also visited discotheques more frequently than controls (chi2 for trend, P = 0.0002). Multiple discotheques during the carnival may have been predominant locations of transmission in this outbreak. Because this risk factor was limited in time, a mass community vaccination campaign was not initiated.


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@article{Hauri2000SerogroupCM, title={Serogroup C meningococcal disease outbreak associated with discotheque attendance during carnival.}, author={Aanja Maria Hauri and Ingrid Ehrhard and Uwe Frank and John Ammer and G. S. E. Fell and Osamah Hamouda and Lyle R. Petersen}, journal={Epidemiology and infection}, year={2000}, volume={124 1}, pages={69-73} }