Serogroup B meningococcal vaccines-an unfinished story.

  title={Serogroup B meningococcal vaccines-an unfinished story.},
  author={Manish Sadarangani and Andrew J Pollard},
  journal={The Lancet. Infectious diseases},
  volume={10 2},
Most invasive meningococcal disease in developed countries is caused by Neisseria meningitidis with a serogroup B capsule. However, despite availability of vaccines for other serogroups since the 1960s, no serogroup B vaccine exists. In this Review we look at the development of serogroup B vaccines over the past 40 years. Outer membrane vesicle vaccines have been successfully used to control geographically isolated epidemics, but most have not been highly immunogenic in young children or… CONTINUE READING


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