Seroepidemiologic survey of captive Old-World primates for antibodies to human and simian retroviruses, and isolation of a lentivirus from sooty mangabeys (Cercocebus atys).

@article{Lowenstine1986SeroepidemiologicSO,
  title={Seroepidemiologic survey of captive Old-World primates for antibodies to human and simian retroviruses, and isolation of a lentivirus from sooty mangabeys (Cercocebus atys).},
  author={Linda J. Lowenstine and Niels C Pedersen and John Higgins and K C Pallis and Atsuko Uyeda and Preston Marx and Nicholas William Lerche and Robert J. Munn and Murray B. Gardner},
  journal={International journal of cancer},
  year={1986},
  volume={38 4},
  pages={563-74}
}
Sera from 526 Old-World monkeys and apes, representing 50 species and 20 genera and living in US zoos and vivaria, were screened for antibodies to HTLV-I, HTLV-III/LAV, and simian-AIDS retrovirus, type I (SRV-I). Sera were screened initially by ELISA, and ELISA-positive sera, as well as ELISA-negative sera from cage contacts, were further tested by Western blotting. A large number of false-positive and a small number of false-negative ELISA sera were identified. Although most true positive… CONTINUE READING