Seroepidemiologic study of human coronavirus OC43 infections in Italy.

  title={Seroepidemiologic study of human coronavirus OC43 infections in Italy.},
  author={Giuseppe Gerna and Ercole Cattaneo and P. Cereda and Maria Grazia Revello},
  journal={Bollettino dell'Istituto sieroterapico milanese},
  volume={57 4},
Human Coronavirus OC43 from suckling mouse brain (SMB) suspension has been adapted to grow in human embryonic lung fibroblast cell cultures. Complement-fixing and hemagglutinating antigens were prepared from infected cell cultures and used in parallel with the same antigens from SMB for a study of the prevalence of OC43 antibody in Northern Italy as well as for the serodiagnosis of recent OC43 infections and reinfections. Results show (i) a higher sensitivity of the hemagglutination-inhibition… CONTINUE READING
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