Seroconversion, neutralising antibodies and protection in bluetongue serotype 8 vaccinated sheep.

  title={Seroconversion, neutralising antibodies and protection in bluetongue serotype 8 vaccinated sheep.},
  author={C A L Oura and James Lionel N. Wood and A J Sanders and Abdelghani Bin-Tarif and Mark R. Henstock and Lorraine Edwards and Tamara Floyd and Heather A Simmons and Carrie Anne Batten},
  volume={27 52},
Bluetongue virus serotype 8 (BTV-8) has caused a major outbreak of disease in cattle and sheep in several countries across northern and western Europe from 2006 to 2008. In 2008 the European Union instigated a mass-vaccination programme in affected countries using whole virus inactivated vaccines. We evaluated vaccinal responses in sheep and the ability of the vaccine to protect against experimental challenge. Sheep vaccinated 10 months previously under field conditions were challenged with BTV… CONTINUE READING

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