Sero-epidemiology of hepatitis B markers in the population of Tuscany, Central Italy, 20 years after the implementation of universal vaccination.

@article{Boccalini2013SeroepidemiologyOH,
  title={Sero-epidemiology of hepatitis B markers in the population of Tuscany, Central Italy, 20 years after the implementation of universal vaccination.},
  author={Sara Boccalini and Elettra Pellegrino and Emila Tiscione and Giovanna Pesavento and Angela Bechini and Miriam Levi and S. Rapi and Stefano Mercurio and Francesco Mannelli and Marta Peruzzi and Cesare Berardi and Paolo Bonanni},
  journal={Human vaccines & immunotherapeutics},
  year={2013},
  volume={9 3},
  pages={
          636-41
        }
}
Italy was one of the first industrialized countries to introduce a program of universal vaccination against hepatitis B in 1991. Twenty years later we verified the impact of universal immunisation on the epidemiology of hepatitis B infection by analyzing the prevalence of specific viral markers (anti-HBs, anti-HBc and HBsAg). The ELISA tests were performed on residual blood samples collected by 0.05% of the resident population aged 1-50 years in Tuscany (Italy). About 63% of subjects aged < 30… CONTINUE READING