Serine protein kinase associated with varicella-zoster virus ORF 47.

@article{Ng1992SerinePK,
  title={Serine protein kinase associated with varicella-zoster virus ORF 47.},
  author={Teresa I. Ng and Charles Grose},
  journal={Virology},
  year={1992},
  volume={191 1},
  pages={9-18}
}
Varicella-zoster virus (VZV) ORF 47 lies in the unique long region of the VZV genome. Sequence homology studies have demonstrated that gene 47 possessed conserved protein kinase motifs. In this study, we investigated the properties of the ORF 47 product. First, a rabbit antiserum was raised against a protein generated from the fusion of the most antigenic ORF 47 domain with Escherichia coli beta-galactosidase. The high-titer antiserum reacted specifically with ORF 47 polypeptides translated in… CONTINUE READING