Serine Protease Activity of Cur l 1 from Curvularia lunata Augments Th2 Response in Mice

@article{Tripathi2008SerinePA,
  title={Serine Protease Activity of Cur l 1 from Curvularia lunata Augments Th2 Response in Mice},
  author={Prabhanshu Tripathi and Neetu Kukreja and Bhanu Pratap Singh and N Arora},
  journal={Journal of Clinical Immunology},
  year={2008},
  volume={29},
  pages={292-302}
}
Studies with mite allergens demonstrated that proteolytic activity augments allergic airway inflammation. This knowledge is limited to few enzyme allergens. The objective of this study is to investigate the effect of serine protease Cur l 1 from Curvularia lunata in airway inflammation/hyper-responsiveness. Cur l 1 was purified and inactivated using a serine protease inhibitor. Balb/c mice were sensitized with enzymatically active Cur l 1 or C. lunata extract. Sensitized mice were given booster… CONTINUE READING
12 Citations
33 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 33 references

Similar Papers

Loading similar papers…