Serine 71 of the glycoprotein HEF is located at the active site of the acetylesterase of influenza C virus

@article{Herrler1988Serine7O,
  title={Serine 71 of the glycoprotein HEF is located at the active site of the acetylesterase of influenza C virus},
  author={Georg Herrler and Gerhard Multhaup and Konrad Beyreuther and H. -D. Klenk},
  journal={Archives of Virology},
  year={1988},
  volume={102},
  pages={269-274}
}
The acetylesterase of influenza C virus has been reported recently to be inhibited by diisopropylfluorophosphate (DFP) [Muchmore EA, Varki A (1987) Science 236: 1293–1295]. As this inhibitor is known to bind covalently to the serine in the active site of serine esterases, we attempted to determine the serine in the active site of the influenza C acetylesterase. Incubation of purified influenza C virus with3H-DFP resulted in the selective labelling of the influenza C glycoprotein HEF. The… CONTINUE READING

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Rat ~l-macroglobulin inhibits hemagglutination by influenza C virus

  • G Herrler, R Geyer, H-P Miiller, S Stirm, H-D Klenk
  • Virus Res
  • 1985
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