Serial time-encoded amplified imaging for real-time observation of fast dynamic phenomena

  title={Serial time-encoded amplified imaging for real-time observation of fast dynamic phenomena},
  author={Keisuke Goda and K. K. Tsia and Bahram Jalali},
Ultrafast real-time optical imaging is an indispensable tool for studying dynamical events such as shock waves, chemical dynamics in living cells, neural activity, laser surgery and microfluidics. [] Key Method Our technique maps a two-dimensional (2D) image into a serial time-domain data stream and simultaneously amplifies the image in the optical domain. We capture an entire 2D image using a single-pixel photodetector and achieve a net image amplification of 25 dB (a factor of 316). This overcomes the…
Single-photon sensitive light-in-fight imaging
A demonstration of the potential of single-photon detector arrays for visualization and rapid characterization of events evolving on picosecond time scales and the extreme sensitivity and short acquisition times pave the way for real-time imaging of ultrafast processes or visualization and tracking of objects hidden from view.
Single-shot real-time femtosecond imaging of temporal focusing
T-CUP’s unprecedented ability to clearly reveal the complex evolution in the shape, intensity, and width of a temporally focused pulse in a single measurement paves the way for single-shot characterization of ultrashort pulses, experimental investigation of nonlinear light-matter interactions, and real-time wavefront engineering for deep-tissue light focusing.
Ultrafast laser-scanning time-stretch imaging at visible wavelengths
This work presents a new pulse-stretching technique, termed free-space angular-chirp-enhanced delay (FACED), with three distinguishing features absent in the prevailing dispersive-fiber-based implementations, and demonstrates not only ultrafast laser-scanning time-stretch imaging with superior bright-field image quality compared with previous work but also, for the first time, MHz fluorescence and colorized time-Stretch microscopy.
Technology: Ultrafast imaging takes on a new design
A technique based on compressed imaging with a streak camera that can video record non-repetitive transient events in two dimensions at 100 billion frames per second, a temporal resolution down to tens of picoseconds is demonstrated.
High-resolution single-shot ultrafast imaging at ten trillion frames per second
Ultrafast imaging is a powerful tool for studying space-time dynamics in photonic material, plasma physics, living cells, and neural activity. Pushing the imaging speed to the quantum limit could
Title Performance of serial time-encoded amplified microscope
Serial time-encoded amplified microscopy (STEAM) is an entirely new imaging modality that enables ultrafast continuous real-time imaging with high sensitivity. By means of optical image
Ultrafast Imaging With Optical Encoding and Compressive Sensing
This paper introduces two methods of alternating direction method of multipliers with total variation regularization (ADMM-TV) and discrete wavelet hard thresholding (DWT-Hrd) for STEAM-based imaging systems and demonstrates that a 10-GHz scan rate can be achieved compared to the conventional 1-GHz microscopy imaging system while maintaining high image reconstruction quality in terms of structural similarity index measurement (SSIM).
Time amplifying techniques towards atomic time resolution
High speed imaging technology has opened applications in many fields, such as collision, detonating, high voltage discharge, disintegration and transfer of phonon and exciton in solid, photosynthesis
A computational approach to real-time image processing for serial time-encoded amplified microscopy
This paper built the prototype system, which including a STEAM camera, a FPGA device and a GPU device, and evaluated its performance in real-time identification of small particles (beads), as virtual biological cells, owing through a microfluidic channel.
Spectro-temporal encoded multiphoton microscopy and fluorescence lifetime imaging at kilohertz frame-rates
High resolution, multi-modal - two-photon fluorescence and fluorescence lifetime (FLIM) – microscopy and imaging flow cytometry with a digitally reconfigurable laser, imaging system and data acquisition system and high speeds should enable high-speed and high-throughput image-assisted cell sorting.


Ultrafast single-shot diffraction imaging of nanoscale dynamics
The transient nanoscale dynamics of materials on femtosecond to picosecond timescales is of great interest in the study of condensed phase dynamics such as crack formation, phase separation and
Amplified wavelength–time transformation for real-time spectroscopy
Real-time spectroscopy provides invaluable information about the evolution of dynamical processes, especially non-repetitive phenomena. Unfortunately, the continuous acquisition of rapidly varying
Amplified dispersive Fourier-transform imaging for ultrafast displacement sensing and barcode reading
Dispersive Fourier transformation is a powerful technique in which the spectrum of an optical pulse is mapped into a time-domain waveform using chromatic dispersion. It replaces a diffraction grating
Three-Dimensional Super-Resolution Imaging by Stochastic Optical Reconstruction Microscopy
3D stochastic optical reconstruction microscopy (STORM) is demonstrated by using optical astigmatism to determine both axial and lateral positions of individual fluorophores with nanometer accuracy, allowing the 3D morphology of nanoscopic cellular structures to be resolved.
Image intensified cameras for high-speed imaging applications that require more than just the high frame-rate
The nature of high-speed or high frame rate imaging results in a short exposure time requiring the object be illuminated with a high brightness light source. In some cases, as in biological studies
Evolution of Ultra-High-Speed CCD Imagers
This paper reviews the high-speed video cameras developed by the authors. A video camera operating at 4,500 frames per second (fps) was developed in 1991. The partial and parallel readout scheme
Microfluidics: Fluid physics at the nanoliter scale
Microfabricated integrated circuits revolutionized computation by vastly reducing the space, labor, and time required for calculations. Microfluidic systems hold similar promise for the large-scale
Molecular fingerprinting with the resolved modes of a femtosecond laser frequency comb
The technique for direct and parallel accessing of stabilized frequency comb modes could find application in high-bandwidth spread-spectrum communications with increased security, high-resolution coherent quantum control, and arbitrary optical waveform synthesis with control at the optical radian level.