Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons

@inproceedings{Weinert2017SerialMC,
  title={Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons},
  author={Tobias Weinert and Natacha Olieric and Robert Y.-S. Cheng and Steffen Br{\"u}nle and Daniel James and Dmitry Ozerov and Dardan Gashi and Laura Vera and May Marsh and Kathrin Jaeger and Florian S N Dworkowski and Ezequiel Panepucci and Shibom Basu and Petr Skopintsev and Andrew S. Dor{\'e} and Tian Geng and R. M. Cooke and Mengning Liang and Andrea E Prota and Val{\'e}rie Panneels and Przemyslaw Nogly and Ulrich Ermler and Gebhard F. X. Schertler and M. J. P. Hennig and Michel O. Steinmetz and Meitian Wang and Joerg Standfuss},
  booktitle={Nature Communications},
  year={2017}
}
Historically, room-temperature structure determination was succeeded by cryo-crystallography to mitigate radiation damage. Here, we demonstrate that serial millisecond crystallography at a synchrotron beamline equipped with high-viscosity injector and high frame-rate detector allows typical crystallographic experiments to be performed at room-temperature… CONTINUE READING