Serial injection of botulinum toxin for muscle imbalance due to regional spasticity in the upper limb.

@article{TurnerStokes2007SerialIO,
  title={Serial injection of botulinum toxin for muscle imbalance due to regional spasticity in the upper limb.},
  author={Lynne Turner-Stokes and Stephen Ashford},
  journal={Disability and rehabilitation},
  year={2007},
  volume={29 23},
  pages={1806-12}
}
BACKGROUND AND PURPOSE Three-dimensional movement in the upper limb presents a challenge for functional management of regional spasticity. Potential toxicity of botulinum toxin limits the number of muscles which may be injected in any one session. Serial injection may offer a solution, but carries theoretical risk of development of resistance due to antibody formation. This article reviews a small case series, gathered in a post-acute neuro-rehabilitation setting, to evaluate the use of serial… CONTINUE READING
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